• Addition of marine omega-3 fatty acids to statins in familial hypercholesterolemia does not affect in vivo or in vitro endothelial function 

      Hande, Liv Nesse; Thunhaug, Hilde; Enebakk, Terje; Ludviksen, Judith K; Pettersen, Kristin; Hovland, Anders; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-29)
      <i>Background</i> - Prestatin trials reported positive effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) in cardiovascular disease, whereas recent studies and meta-analyses have not reproduced these results. The effect of n-3 PUFA in patients with familial hypercholesterolemia (FH), a group with particularly high risk of cardiovascular disease, is not well established.<p><p> <i>Objective</i> ...
    • Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model 

      Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Ludviksen, Judith K; Mollnes, Tom Eirik; Lappegård, Knut Tore; Hovland, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-29)
      <i>Introduction</i> - Even if proprotein convertase subtilisin/kexin type 9 inhibitors have replaced lipoprotein apheresis in many patients, lipoprotein apheresis still is an important option in homozygous familial hypercholesterolemia, progressive atherosclerosis or when removal of lipoprotein(a) is indicated. Additional possible favorable effects beyond lipid lowering could include changes in ...
    • Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) – an ex vivo study with blood from a C5-deficient individual 

      Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Bergseth, Grete; Brekke, Ole-Lars; Mollnes, Tom Eirik; Lappegård, Knut Tore; Hovland, Anders (Journal article; Tidsskriftartikkel, 2018)
      The aim of the study was to investigate the role of complement factor 5 (C5) in reactions elicited by plasma separation using blood from a C5‐deficient (C5D) individual, comparing it to C5‐deficient blood reconstituted with C5 (C5DR) and blood from healthy donors. Blood was circulated through an <i>ex vivo</i> plasma separation model. Leukocyte CD11b expression and leukocyte–platelet conjugates were ...
    • Health-related quality of life on tele-monitoring for users with pacemakers 6 months after implant: the NORDLAND study, a randomized trial 

      Lopez-Villegas, Antonio; Catalán-Matamoros, Daniel; Lopez-Liria, Remedios; Enebakk, Terje; Thunhaug, Hilde; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      <i>Background</i>: With an ageing population and widening indications for pacemakers implantation, the number of persons carrying an implant is steadily increasing. The routine follow-up is thus a heavy burden for the respective NHS as well as for the patients and their relatives. Most of them of the studies have been performed in densely populated areas and nearby to the hospital. It is thus ...
    • Telemonitoring and quality of life in patients after 12 months following a pacemaker implant: The Nordland study, a randomised trial 

      Lopez-Liria, Remedios; Lopez-Villegas, Antonio; Enebakk, Terje; Thunhaug, Hilde; Lappegård, Knut Tore; Catalán-Matamoros, Daniel (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-05)
      The purpose of this study was to analyse the health-related quality of life (HRQoL) of patients followed up using a remote device-monitoring system (TM) compared to patients followed up through standard outpatient visits (HM), 12 months after the implantation of a pacemaker. This was a trial design that used the EuroQol-5D Questionnaire and the Minnesota Living with Heart Failure Questionnaire (MLHF). ...